SIBO - Small Intestinal Bacterial Overgrowth
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2024 Research Articles

Related
  • Italian guidelines for the management of irritable bowel syndrome in children and adolescents : Joint Consensus from the Italian Societies of: Gastroenterology, Hepatology and Pediatric Nutrition (SIGENP), Pediatrics (SIP), Gastroenterology and Endoscopy (SIGE) and Neurogastroenterology and Motility (SINGEM)  PMID: 38486305
  • Psychological distress in individuals with irritable bowel syndrome: the roles of body image and self-criticism. PMID: 38562654
  • Characterization of the Small Bowel Microbiome Reveals Different Profiles in Human Subjects Who Are Overweight or Have Obesity  PMID: 38578969
  • Functional Abdominal Bloating and Gut Microbiota: An Update  PMID: 39203511
    • Summary: This 12-study review found that “restoring a balanced microbiome appears to be the most promising solution” via “probiotics, prebiotics, antibiotics such as rifaximin or dietary modifications”, as well as “neuromodulators, and brain-gut behavioral therapies (i.e., cognitive-behavioral therapy)”.
  • ​Third generation sequencing analysis detects significant differences in duodenal microbiome composition between functional dyspepsia patients and control subjects  PMID: 39491051
  • Food Retention at Endoscopy Among Adults Using Glucagon-Like Peptide-1 Receptor Agonists PMID: 39352703

Overview
  • Small Intestinal Bacterial Overgrowth  PMID: 31536241
  • Critical appraisal of the SIBO hypothesis and breath testing: A clinical practice update endorsed by the European society of neurogastroenterology and motility (ESNM) and the American neurogastroenterology and motility society (ANMS)  PMID: 38798120
  • [SIBO, from myth to reality]  PMID: 39237384
  • [Small intestinal bacterial overgrowth (SIBO) - Therapy, nutrition, microbiome]  PMID: 39208859

Causes/ Risk Factors 
Diseases
  • Liquid Thyroxine Improves Outcomes in Hypothyroid Patients with Small Intestinal Bacterial Overgrowth and Irritable Bowel Syndrome  PMID: 38490469  PMID: 38490469
  • Small Bowel Diverticulosis in an Elderly Patient Presenting With Obstruction and Intestinal Dysmotility: A Case Report  PMID: 39539876
Drugs/medication 
  • A multi-national survey to identify clinicians' perspectives concerning Proton Pump inhibitors in patients with systemic sclerosis  PMID: 38430623
  • A Study on the Glucose Breath Test Positivity Rate and Occurrence of Small Intestine Bacterial Overgrowth-Related Symptoms Caused by Long-Term Use of Proton Pump Inhibitor (PPI) Versus Potassium-Competitive Acid Blocker (P-CAB) in Elderly Patients: SIBO Between PPI and P-CAB  PMID: 39502577
    • Summary: “Long-term use of gastric acid suppressants resulted in positive GBT [SIBO] in approximately 30% of patients, and the risk was particularly high in elderly patients. The occurrence of SIBO-related symptoms was significant in long-term use of PPIs and in patients with positive GBT.”
Surgery
  • Effects of Probiotic Use on Gastrointestinal Symptoms in the Late Postoperative Period of Bariatric Surgery: A Cross-Over, Randomized, Triple-Blind, Placebo-Controlled Study  PMID: 38418752
  • Prospective Monitoring of Small Intestinal Bacterial Overgrowth After Gastric Bypass: Clinical, Biological, and Gas Chromatographic Aspects  PMID: 38300481
  • Blind Loop Syndrome  PMID: 36508549
  • Modified Rosi-Cahill technique after left extended colectomy for splenic flexure advanced tumors  PMID: 39031212
  • Use of Probiotics and Synbiotics in the Treatment of Small Intestinal Bacterial Overgrowth (SIBO) and Other Gastrointestinal Symptoms After Metabolic Bariatric Surgery: a Systematic Review and Meta-Analysis  PMID: 39607556
​

Pathophysiology
  • Small intestinal microbiota: from taxonomic composition to metabolism  PMID: 38503579
  • Small Intestine Bacterial Overgrowth is associated with increased Campylobacter and epithelial injury in duodenal biopsies of Bangladeshi children.    PMID: 38536881
  • Fecal Coprococcus, hidden behind abdominal symptoms in patients with small intestinal bacterial overgrowth  PMID: 38796441
  • Intestinal Methanogen Overgrowth (IMO) Is Associated with Delayed Small Bowel and Colonic Transit Time (TT) on the Wireless Motility Capsule (WMC)  PMID: 39068378
  • Identification of SIBO Subtypes along with Nutritional Status and Diet as Key Elements of SIBO Therapy  PMID: 39000446
  • Symptom Profile of Patients With Intestinal Methanogen Overgrowth: A Systematic Review and Meta-analysis  PMID: 39147218
    • Summary: Review of 19 studies analyzing symptoms present in those with IMO (Methane-SIBO)
      • bloating (78%)
      • constipation (51%)
      • diarrhea (33%)
      • abdominal pain (65%)
      • nausea (30%)
      • flatulence (56%)
  • ​Cytolethal distending toxin B inoculation leads to distinct gut microtypes and IBS-D-like microRNA-mediated gene expression changes in a rodent model  PMID: 38108386


Associated Conditions
  • Small Intestinal Bacterial Overgrowth (SIBO) and Twelve Groups of Related Diseases-Current State of Knowledge  PMID: 38790992​
Alzheimer
  • Association between small intestine bacterial overgrowth and psychiatric disorders  PMID: 39497810
    • Summary: “These findings highlight the importance of tryptophan metabolism in the gut-brain axis and suggest that addressing SIBO and its impact on tryptophan metabolism could be a potential therapeutic avenue for managing and understanding these complex disorders [Parkinson’s and Alzheimer’s disease, depression, schizophrenia, and autism spectrum disorder].
Autism
  • Association between small intestine bacterial overgrowth and psychiatric disorders  PMID: 39497810
    • Summary: “These findings highlight the importance of tryptophan metabolism in the gut-brain axis and suggest that addressing SIBO and its impact on tryptophan metabolism could be a potential therapeutic avenue for managing and understanding these complex disorders [Parkinson’s and Alzheimer’s disease, depression, schizophrenia, and autism spectrum disorder].
Brain Fog
  • Brain Fog in Gastrointestinal Disorders: Small Intestinal Bacterial Overgrowth, Gastroparesis, Irritable Bowel Syndrome  PMID: 39495803
Children (Pediatric)
  • Factors associated with D-lactic acidosis in pediatric intestinal failure: A case-control study  PMID: 38374557
  • Assessment of Biochemical, Inflammatory Biomarkers and Ultra-Processed Food Consumption in Children with Small Intestinal Bacterial Overgrowth: A Cross-Sectional Study  PMID: 39125359
  • Pediatric Chronic Intestinal Failure: Something Moving?  PMID: 39275281
Cystic Fibrosis
  • The gastrointestinal microbiome, small bowel bacterial overgrowth, and microbiome modulators in cystic fibrosis  PMID: 39105345
Dental/Oral Health
  • Oral Health and "Modern" Digestive Diseases: Pathophysiologic and Etiologic Factors  PMID: 39200318
Depression
  • Association between small intestine bacterial overgrowth and psychiatric disorders  PMID: 39497810
    • Summary: “These findings highlight the importance of tryptophan metabolism in the gut-brain axis and suggest that addressing SIBO and its impact on tryptophan metabolism could be a potential therapeutic avenue for managing and understanding these complex disorders [Parkinson’s and Alzheimer’s disease, depression, schizophrenia, and autism spectrum disorder].
Diabetes
  • Small intestinal bacterial overgrowth in diabetic gastroenteropathy  PMID: 38651669  
Diverticulosis
  • Small Bowel Diverticulosis in an Elderly Patient Presenting With Obstruction and Intestinal Dysmotility: A Case Report  PMID: 39539876
Gastric Bypass
  • Prospective Monitoring of Small Intestinal Bacterial Overgrowth After Gastric Bypass: Clinical, Biological, and Gas Chromatographic Aspects  PMID: 38300481
  • Effects of Probiotic Use on Gastrointestinal Symptoms in the Late Postoperative Period of Bariatric Surgery: A Cross-Over, Randomized, Triple-Blind, Placebo-Controlled Study  PMID: 38418752
  • Use of Probiotics and Synbiotics in the Treatment of Small Intestinal Bacterial Overgrowth (SIBO) and Other Gastrointestinal Symptoms After Metabolic Bariatric Surgery: a Systematic Review and Meta-Analysis  PMID: 39607556
​GERD
  • The Lactulose Breath Test Can Predict Refractory Gastroesophageal Reflux Disease by Measuring Bacterial Overgrowth in the Small Intestine  PMID: 38896424
  • Impacts of intestinal fermentation on gastroesophageal reflux disease: can the tail wag the dog?  PMID: 39573864
Halitosis NEW
  • Therapeutic efficacy of a probiotic preparation on idiopathic halitosis: a retrospective observational study  PMID: 39496205
    • Summary: “Our findings suggest that idiopathic halitosis is an extra-oral condition which mostly originates from the small intestine. SIBO is one of its underlying causes. The probiotic preparation [Bifidobacterium triple viable capsule for two months] can effectively improve idiopathic halitosis, probably through its impact on SIBO.”
H. pylori
  • Helicobacter pylori infection and Parkinson's Disease: etiology, pathogenesis and levodopa bioavailability  PMID: 38166953
  • Influence of Helicobacter pylori Infection and Eradication on Small Intestinal Bacterial Overgrowth and Abdominal Symptoms  PMID: 38363519
Hypothyroid
  • Liquid Thyroxine Improves Outcomes in Hypothyroid Patients with Small Intestinal Bacterial Overgrowth and Irritable Bowel Syndrome PMID: 38490469
IBD (Inflammatory Bowel Disease)
  • The Association of Extra-oral Halitosis With Small Intestinal Bacterial Overgrowth in Inflammatory Bowel Disease  PMID: 38696141
  • Anti-CdtB and anti-vinculin antibodies to diagnose irritable bowel syndrome in inflammatory bowel disease patients   PMID: 39627697
IBS (Irritable Bowel Syndrome)
  • The IBS and SIBO dilemma: Here we go again  PMID: 39218737
  • Differences in clinical manifestations and the fecal microbiome between irritable bowel syndrome and small intestinal bacterial overgrowth  PMID: 39043536
Intestinal Failure (pediatric)
  • Factors associated with D-lactic acidosis in pediatric intestinal failure: A case-control study  PMID: 38374557
  • Are enteral devices risk factors for central line-associated bloodstream infections in children with intestinal failure?  PMID: 39742591
Lactose Malabsorption
  • Rifaximin-Alpha Increases Lactase Activity in Patients with Irritable Bowel Syndrome Without Constipation and Small Intestinal Bacterial Overgrowth  PMID: 39641896
Liver Disease
  • Efficacy and Safety of a Probiotic Containing Saccharomyces boulardii CNCM I-745 in the Treatment of Small Intestinal Bacterial Overgrowth in Decompensated Cirrhosis: Randomized, Placebo-Controlled Study  PMID: 38337613
  • Dysbiosis and nutrition in steatotic liver disease: addressing the unrecognized small intestinal bacterial overgrowth (SIBO) challenge  PMID: 38499938
  • Small intestinal bacterial overgrowth in obese patients with biopsy-confirmed metabolic dysfunction-associated steatotic liver disease: a cross-sectional study  PMID: 38854668
  • Impact of small intestinal bacterial overgrowth on systemic inflammation, circulatory and renal function, and liver fibrosis in patients with cirrhosis and ascites  PMID: 38779647
  • MASLD can cause halitosis by small intestinal bacterial overgrowth  PMID: 38764349
  • Small intestinal bacterial overgrowth and metabolic dysfunction-associated steatotic liver disease PMID: 39742106
    • Summary: “this meta-analyses provides strong evidence that SIBO may contribute to the development and progression of MASLD [Metabolic-Associated Steatotic Liver Disease].”
Parkinson’s
  • Helicobacter pylori infection and Parkinson's Disease: etiology, pathogenesis and levodopa bioavailability  PMID: 38166953
  • A review of the gastrointestinal, olfactory, and skin abnormalities in patients with Parkinson's disease  PMID: 38195133
  • Consensus practice recommendations for management of gastrointestinal dysfunction in Parkinson disease  PMID: 38729797
  • The Gut Microbiota in Parkinson Disease: Interactions with Drugs and Potential for Therapeutic Applications  PMID: 38570412
  • Association between small intestine bacterial overgrowth and psychiatric disorders  PMID: 39497810
    • Summary: “These findings highlight the importance of tryptophan metabolism in the gut-brain axis and suggest that addressing SIBO and its impact on tryptophan metabolism could be a potential therapeutic avenue for managing and understanding these complex disorders [Parkinson’s and Alzheimer’s disease, depression, schizophrenia, and autism spectrum disorder].
  • Gut-Brain Axis a Key Player to Control Gut Dysbiosis in Neurological Diseases  PMID: 37851313
Rosacea
  • Evaluation of Helicobacter pylori and Small Intestinal Bacterial Overgrowth in Subjects With Rosacea  PMID: 39583431
Systemic Sclerosis
  • [Severe small bowel involvement and chronic intestinal pseudo-obstruction in systemic sclerosis (scleroderma): Pathophysiological, diagnostic and therapeutic basis, including parenteral nutrition]  PMID: 38388303
  • Diffuse Gastrointestinal Motor Compromise in Patients with Scleroderma: Utility of Minimally Invasive Techniques  PMID: 37982941
  • A multi-national survey to identify clinicians' perspectives concerning Proton Pump inhibitors in patients with systemic sclerosis  PMID: 38430623
Thyroid
  • Evaluation of the therapeutic efficacy of different doses of LT4 in pregnant women with high-normal TSH levels and TPOAb positivity in the first half of pregnancy  PMID: 38600581


Testing
  • Gastric, small bowel and colonic motility and breath-testing  /doi.10.1016/j.mpmed.2024.01.004​
  • Critical appraisal of the SIBO hypothesis and breath testing: A clinical practice update endorsed by the European society of neurogastroenterology and motility (ESNM) and the American neurogastroenterology and motility society (ANMS)  PMID: 38798120
  • Small Intestinal Bacterial Overgrowth (SIBO), a clinically overdiagnosed entity?  PMID: 38719183
  • Glucose breath test for the detection of small intestine bacterial overgrowth: Impact of diet prior to the test  PMID: 38606691
  • Capsules for the Diagnosis and Treatment of Gastrointestinal Motility Disorders- A Game Changer  PMID: 38630422
  • Detection capacity of small intestine bacterial or methanogen overgrowth by lactose and fructose breath testing in the adult population  PMID: 39252801
  • Validation of a Hand-Held Point-of-Care Device to Measure Breath Hydrogen and Its Utility in Detecting Response to Antibiotic Treatment  PMID: 39127844
    • Summary: This study compared FoodMarble AIRE® to existing mail-in kits in patients suspected to have SIBO.
      Results: “Substantial agreement was demonstrated between AIRE and the mail-in kits for the performance of lactulose hydrogen breath tests.”
  • ​Evaluation of a Novel Smart Capsule Bacterial Detection System Device for Diagnosis of Small Intestinal Bacterial Overgrowth  PMID: 39587802
    • Summary: “These results demonstrate the potential utility of SCBDS [smart capsule bacterial detection system] device to aid SIBO diagnosis as a simple and non-invasive tool that merits further clinical validation.”
  • The prevalence of small intestine bacterial overgrowth in irritable bowel syndrome is much higher with lactulose than glucose breath test: Results of a retrospective monocentric study  PMID: 39426620


Methane
  • The Lactulose Breath Test Can Predict Refractory Gastroesophageal Reflux Disease by Measuring Bacterial Overgrowth in the Small Intestine  PMID: 38896424


​Treatment 
  • Common questions and rationale answers about the intestinal bacterial overgrowth syndrome (SIBO)  PMID: 38852778
  • The importance of food quality, gut motility, and microbiome in SIBO development and treatment  PMID: 38657418
Antibiotics
  • Antibiotics for Dyspepsia: Hp, SIBO, IMO, or Something Else?  PMID: 38363520
  • Symptomatic Response to Antibiotics in Patients With Small Intestinal Bacterial Overgrowth: A Systematic Review and Meta-analysis  PMID: 38173154
  • Amoxicillin Clavulanate  PMID: 30844191
    • Summary: “the efficacy of amoxicillin-clavulanate in treating SIBO approximates 50%”
  • Rifaximin and alternative agents in the management of irritable bowel syndrome: A comprehensive review  PMID: 39041415
  • Low dose rifaximin combined with N-acetylcysteine is superior to rifaximin alone in a rat model of IBS-D: a randomized trial  PMID: 39103611
    • Summary: (rat study) “poor solubility [of Rifaximin] may limit its efficacy against microbes in the mucus layer, e.g. Escherichia coli. Here we evaluate adding the mucolytic N-acetylcysteine (NAC) to improve rifaximin efficacy.  …combining rifaximin with NAC had significant synergistic effects in reducing E. coli levels.”
      Dr. Pimentel and I discuss the “special formulation” of NAC that he used in a recent interview. Watch it Here (NAC discussion is at 1:21 hours, study results at 20:34 min)
  • Rifaximin-Alpha Increases Lactase Activity in Patients with Irritable Bowel Syndrome Without Constipation and Small Intestinal Bacterial Overgrowth  PMID: 39641896
  • Rifaximin  PMID: 30000968
  • Rifaximin prophylaxis causes resistance to the last-resort antibiotic daptomycin  PMID: 39443798
  • A Pilot Study of the Effectiveness of a Short Course of Rifaximin 2200 mg/day on Abdominal Symptoms and its Effects on Quality of Life in Patients with Moderate to Severe Diarrhea-Predominant Irritable Bowel Syndrome PMID: 39476291
    • Summary: This study used a higher dose of Rifaximin, 2200mg x 10 days vs the standard SIBO dose of 1650 mg/d x 14 days, for IBS-diarrrhea (SIBO was not tested), which resulted in significant improvement in symptoms, no serious adverse effects, and 94.9% adherence rate.
Rifaximin
  • Drugs of the future for diarrhea-predominant irritable bowel syndrome: an overview of current investigational drugs  PMID: 38366822
  • Effect of Trimebutine and Rifaximin on Breath Hydrogen and Methane by Glucose Breath Test in Patients With Functional Bloating: A Randomized Double-blind Clinical Trial  PMID: 38576371
Trimebutine Maleate
  • Effect of Trimebutine and Rifaximin on Breath Hydrogen and Methane by Glucose Breath Test in Patients With Functional Bloating: A Randomized Double-blind Clinical Trial  PMID: 38576371  
Herbal Antibiotics
  • Do Herbal Supplements and Probiotics Complement Antibiotics and Diet in the Management of SIBO? A Randomized Clinical Trial  PMID: 38613116
Elemental Diet
  • Elemental Diet as a Therapeutic Modality: A Comprehensive Review  PMID: 39001958
Fecal Microbiota Transplantation (FMT)
  • The impact of small intestinal bacterial overgrowth on the efficacy of fecal microbiota transplantation in patients with chronic constipation  PMID: 39194187
Probiotics
  • Do Herbal Supplements and Probiotics Complement Antibiotics and Diet in the Management of SIBO? A Randomized Clinical Trial  PMID: 38613116
  • Effects of Probiotic Use on Gastrointestinal Symptoms in the Late Postoperative Period of Bariatric Surgery: A Cross-Over, Randomized, Triple-Blind, Placebo-Controlled Study  PMID: 38418752
  • Probiotics and Prebiotics in Subclinical Hypothyroidism of Pregnancy with Small Intestinal Bacterial Overgrowth  PMID: 37032411
  • Therapeutic efficacy of a probiotic preparation on idiopathic halitosis: a retrospective observational study  PMID: 39496205
    • Summary: “Our findings suggest that idiopathic halitosis is an extra-oral condition which mostly originates from the small intestine. SIBO is one of its underlying causes. The probiotic preparation [Bifidobacterium triple viable capsule for two months] can effectively improve idiopathic halitosis, probably through its impact on SIBO.”
  • Use of Probiotics and Synbiotics in the Treatment of Small Intestinal Bacterial Overgrowth (SIBO) and Other Gastrointestinal Symptoms After Metabolic Bariatric Surgery: a Systematic Review and Meta-Analysis  PMID: 39607556 
Prokinetics
  • Efficacy and Safety of a Probiotic Containing Saccharomyces boulardii CNCM I-745 in the Treatment of Small Intestinal Bacterial Overgrowth in Decompensated Cirrhosis: Randomized, Placebo-Controlled Study  PMID: 38337613
  • Clinical outcomes before and after prucalopride treatment: an observational study in patients with chronic idiopathic constipation in the USA  PMID: 38357940
  • Safety and Effectiveness of Prucalopride in Children with Functional Constipation with and without Upper Symptoms  PMID: 38175354
  • Effect of Iberogast (STW5) on tolerance to colonic gas in patients with irritable bowel syndrome: A randomized, double-blind, placebo control clinical trial  PMID: 38361151
  • 5-HT4 receptor agonists treatment reduces tau pathology and behavioral deficit in the PS19 mouse model of tauopathy  PMID: 38638303
  • Association between a selective 5-HT4 receptor agonist and incidence of major depressive disorder: emulated target trial  PMID: 39109752
    • Summary: “Treatment with prucalopride was associated with significantly lower incidence of depression … Significantly lower risks of all mood disorders and psychosis were also observed. … These findings support preclinical data and suggest a role for 5-HT4R agonists [prucalopride] as novel agents in the prevention of major depression.”
  • Gastroparesis treatment options metoclopramide and prucalopride: analysis of the FDA Adverse Event Reporting System (FAERS) database  PMID: 38995209
    • Summary: “Analysis of 865 reports [of adverse events] on prucalopride revealed
      • headache (n = 120, 13.9%)
      • diarrhea (n = 116, 13.4%)
      • abdominal pain (n = 100, 11.6%)
      • dystonia (n=22, 2.5%)”
  • Prokinetic effect of erythromycin in the management of gastroparesis in critically ill patients-our experience and literature review  PMID: 39314225
Diet
  • Food Intolerances, Food Allergies and IBS: Lights and Shadows  PMID: 38257158
  • The Role of Diet in the Management of Irritable Bowel Syndrome: A Comprehensive Review  PMID: 38496157
  • [Small intestinal bacterial overgrowth (SIBO) - Therapy, nutrition, microbiome]  PMID: 39208859
Diet: FODMAP Diet
  • The Role of the FODMAP Diet in IBS  PMID: 38337655
  • Alterations in gut microbiota caused by major depressive disorder or a low FODMAP diet and where they overlap  PMID: 38260072
  • Can we predict who will respond to a low-FODMAP diet in irritable bowel syndrome?  PMID: 38238032
  • Nutrition and Disorders of Gut-Brain Interaction  PMID: 38202005
  • Effect of fibre fortification of low FODMAP pasta  PMID: 38225882
  • Efficacy and Findings of a Blinded Randomized Reintroduction Phase for the Low FODMAP Diet in Irritable Bowel Syndrome  PMID: 38401741
  • Fructan Concentrations in Cooked Cereal Grains as a Nutritional Consideration for Low-FODMAP Diet  PMID: 38257195
  • Quality characteristics of cereal-based foods enriched with different degree of polymerization inulin: A review  PMID: 38431396
  • Diet low in fodmaps: fundamentals, evidence and controversies  PMID: 38493009
  • Exploration of differential responses to FODMAPs and gluten in people with irritable bowel syndrome- a double-blind randomized cross-over challenge study  PMID: 38347192
  • Fructose malabsorption and fructan malabsorption are associated in patients with irritable bowel syndrome  PMID: 38654193
  • Effect of the Low Fermentable Oligosaccharides, Disaccharides, Monosaccharides, and Polyols (FODMAP) Diet on Control of Pediatric Irritable Bowel Syndrome and Quality of Life Among a Sample of Egyptian Children: A Randomized Controlled Clinical Trial.  PMID: 38910620
  • The low-FODMAP diet PMID: 38906802
  • Changes in Fecal Short-Chain Fatty Acids in IBS Patients and Effects of Different Interventions: A Systematic Review and Meta-Analysis.  PMID: 38892659  
  • Is the Mediterranean Low Fodmap Diet Effective in Managing Irritable Bowel Syndrome Symptoms and Gut Microbiota? An Innovative Research Protocol.  PMID: 38892525
  • A diet low in fermentable oligo-, di-, monosaccharides and polyols improves abdominal and overall symptoms in persons with all subtypes of irritable bowel syndrome.  PMID: 38887150  
  • Unveiling the dynamics of gut microbial interactions: a review of dietary impact and precision nutrition in gastrointestinal health.  PMID: 38873568 
  • [Gastrointestinal symptoms and dietary intake of patients with irritable bowel syndrome following a low FODMAP diet].  PMID: 38809220
  • Causative Factors, Clinical Manifestations, and Therapeutic Strategies for Irritable Bowel Syndrome.  PMID: 38779277
  • Evolution, adaptation, and new applications of the FODMAP diet.  PMID: 38770353
  • The efficacy and real-world effectiveness of a diet low in fermentable oligo-, di-, monosaccharides and polyols in irritable bowel syndrome: A systematic review and meta-analysis.  PMID: 38754307  
  • Global research trend and hotspot in the low FODMAP diet: a bibliometric analysis.  PMID: 38741213
  • Is a Simplified, Less Restrictive Low FODMAP Diet Possible? Results from a Double-Blind, Pilot Randomized Controlled Trial.  PMID: 38729393
  • All FODMAPs Aren't Created Equal: Results of a Randomized Reintroduction Trial in Patients With Irritable Bowel Syndrome.  PMID: 38729390
  • A Multicenter Randomized Controlled Trial of Microbiome-Based Artificial Intelligence-Assisted Personalized Diet vs Low-Fermentable Oligosaccharides, Disaccharides, Monosaccharides, and Polyols Diet: A Novel Approach for the Management of Irritable Bowel Syndrome.  PMID: 38717025
  • Effects of a low FODMAP diet on the symptom management of patients with irritable bowel syndrome: a systematic umbrella review with the meta-analysis of clinical trials.  PMID: 38711328
  • Nutritional safety and status following a 12-week strict low FODMAP diet in patients with irritable bowel syndrome.  PMID: 38689453
  • Coffee, Alcohol, and Artificial Sweeteners Have Temporal Associations with Gastrointestinal Symptoms.  PMID: 38662159
  • Production, modification and degradation of fructans and fructooligosacharides by enzymes originated from plants.  PMID: 38649077
  • Managing irritable bowel syndrome: balancing diet and pharmacotherapy.  PMID: 38643783
  • A low FODMAP diet plus traditional dietary advice versus a low-carbohydrate diet versus pharmacological treatment in irritable bowel syndrome (CARIBS): a single-centre, single-blind, randomised controlled trial.  PMID: 38643782
  • Efficacy of a Low-FODMAP Diet for Coeliac Patients with Persistent IBS-like Symptoms despite a Gluten-Free Diet: A Systematic Review.  PMID: 38613127
  • Low-FODMAP diet on postprandial distress syndrome type of functional dyspepsia with mixed type of irritable bowel syndrome patient: A case report  PMID: 39280305
  • A Starch- and Sucrose-Reduced Diet Has Similar Efficiency as Low FODMAP in IBS-A Randomized Non-Inferiority Study  PMID: 39275354
  • Relationship between Markers of Gut Barrier Function and Erythrocyte Membrane PUFAs in Diarrhea-Predominant IBS Patients Undergoing a Low-FODMAP Diet  PMID: 39203842
  • Microbiome-driven IBS metabotypes influence response to the low FODMAP diet: insights from the faecal volatome  PMID: 39173527
  • Patients' experiences of dietary changes during a structured dietary intervention for irritable bowel syndrome  PMID: 39138906
  • Nutritional Interventions in Adult Patients With Irritable Bowel Syndrome: An Umbrella Review of Systematic Reviews and Meta-analyses of Randomized Clinical Trials  PMID: 39110917
  • DOMINO trial post hoc analysis: evaluation of the diet effects on symptoms in IBS subtypes  PMID: 39086991
  • Predictors of response to a dietary intervention in patients with irritable bowel syndrome  PMID: 39029788
  • Sourdough Bread Quality: Facts and Factors  PMID: 38998638
  • Predicting Response to Low Fermentable Oligo-, Di-, Mono-saccharides, and Polyols Diet in Patients With Abdominal Bloating Using Hydrogen Methane Breath Test: Is a Spot Sample Enough?  PMID: 38972871
  • FODMAP Diet in Celiac Disease and Gluten-Related Disorders.  PMID: 39683583
  • Low FODMAP diets-Boon or bane for individuals with GI disorders.  PMID: 39529351
  • Gut-Brain Axis and Psychopathology: Exploring the Impact of Diet with a Focus on the Low-FODMAP Approach.  PMID: 39458509
  • Use of Carbohydrate (CHO), Gluten-Free, and FODMAP-Free Diets to Prevent Gastrointestinal Symptoms in Endurance Athletes: A Systematic Review.  PMID: 39599638
  • Adapted Low-FODMAP Diet in IBS Patients with and without Fibromyalgia: Long-Term Adherence and Outcomes.  PMID: 39408383
  • Efficacy and Safety of a Low-FODMAP Diet in Combination with a Gluten-Free Diet for Adult Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis.  PMID: 39407084
  • A service evaluation of FODMAP restriction, FODMAP reintroduction and long-term follow-up in the dietary management of irritable bowel syndrome.  PMID: 39498596
  • Dietary management of irritable bowel syndrome: considerations, challenges, and solutions.  PMID: 39521003
  • Practices and Barriers in Implementing the Low FODMAP Diet for Irritable Bowel Syndrome Among Malaysian Dietitians: A Qualitative Study.  PMID: 39519430 
  • Comparison of 4-week versus 8-week dietitian-led FODMAP diet group education sessions in tertiary care clinical practice for irritable bowel syndrome: A service evaluation  PMID: 39380330
  • Gluten-Free Diet for Fashion or Necessity? Review with New Speculations on Irritable Bowel Syndrome-like Disorders.  PMID: 39683629
  • Impact of HADS Anxiety and Depression Scores on the Efficacy of Dietary Interventions for Irritable Bowel Syndrome.  PMID: 39392338
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