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1/29/2026

Q&A: Previous Food Poisoning; Stool Test Negative, BMs Still Abnormal - What to Test Next?

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This video delves into the connection between food poisoning and SIBO (Small Intestinal Bacterial Overgrowth), discussing various diagnostic methods and their nuances.

Key Discussions and Takeaways:
  • SIBO as a Consequence of Food Poisoning: The video highlights that food poisoning can be a primary cause of SIBO, often manifesting as a delayed reaction months afterwards.
  • Diagnostic Tools for SIBO:
    • Breath Test: Mentioned as a standard diagnostic method for SIBO.
    • IBS Smart Test: This blood test is specifically noted as a way to diagnose SIBO that may stem from food poisoning.
  • Stool Testing Sensitivity:
    • The video contrasts the sensitivity of stool testing from different laboratories.
    • LabCorp and Quest Diagnostics are cited as having stool tests that are less sensitive for parasites and functional stool testing.
    • Tests from GI Map, Genova, and Vibrant America are mentioned as potentially more sensitive options for functional stool testing.
  • Timing and Stool Testing for Food Poisoning: It's emphasized that pathogenic organisms responsible for food poisoning are typically cleared from the stool relatively quickly after the initial illness. Therefore, a stool test performed after the event might not detect the original pathogen.
  • Direct-to-Consumer Functional Stool Testing:
    • Rupa Labs is highlighted as a service where individuals can order their own functional stool testing.
    • ​While self-ordering is possible, the interpretation of results still requires consultation with a healthcare practitioner.

Products mentioned:
- IBS-smart test
- SIBO breath tests
- Stool tests:
  • https://www.rupahealth.com/allison-siebecker (Rupa)
  • http://www.directlabs.com/sibo (Direct labs)
  • https://truehealthlabs.com/product-category/alphabetical-2/sibo/#siboinfo (True Health)

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1/22/2026

SIBO Q&A after watching Dr. Pimentel SIBO Update 2025

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This video features Dr. Allison Siebecker answering live questions after the watch party viewing of Dr. Pimentel's 2025 SIBO Update recording, with host Shivan Sarna, Various SIBO and related topics are covered.  
-- Watch Dr. Pimentel's 2025 SIBO Update 
-- Mentioned class: watch Dr. Siebecker's Gut Supplement Masterclass (free) 

Key Discussions:
  1. Understanding Prokinetics:
  • Prokinetics are agents that stimulate the migrating motor complex, crucial for preventing SIBO by clearing debris from the small intestine.
  • They can be herbal, supplemental, or prescription-based, with options like ginger, Iberogast, and Motegrity being discussed.

     2.  Antibiotics for SIBO and IBS:
  • The episode clarifies that Dr. Pimentel and his team did not create rifaximin but were among the first to explore its use for SIBO and IBS.
  • Discussion on the effectiveness of antibiotics like neomycin and metronidazole for methanogen overgrowth (IMO/Methane-SIBO).
   
    3. New Elemental Diet Treatment:
  • The mBiota Elemental diet, developed by Dr. Pimentel and Dr. Ali Rezaie, is highlighted as a significant advancement in treating SIBO.
  • The elemental diet is noted for its effectiveness against hydrogen SIBO and methane SIBO/IMO (Intestinal Methanogen Overgrowth).

   4.  And More:
  • Various other SIBO and GI topics are raised in the live questions. 

Takeaways:
  • Prokinetics play a vital role in managing SIBO by enhancing gut motility.
  • Rifaximin remains a cornerstone in SIBO treatment, with ongoing research into its applications.
  • The mBiota Elemental diet offers a promising alternative for patients with SIBO, IMO, ISO and IBS.

Conclusion:
  • This video concludes with a message of hope and encouragement for those dealing with SIBO and IBS, emphasizing the importance of staying informed and proactive in treatment.

Practitioner MENTIONED:
- Debbie Steinbock
 
- Dr. Siebecker's webinar with Debbie (YouTube)  

PRODUCTS MENTIONED:

- mBiota Elemental Diet: (use code SIBO50 for $50 Off or code SIBO for $25 off - one time use)
- Other Elemental Diets: (exclusive pricing at Fullscript)

- NAC Sustain by Jarrow: (exclusive pricing at Fullscript) or (Amazon)

- IBS Shield
- IBS Shield Glycerin
- Iberogast
- Iberogast Pills
- Other Herbal Prokinetics: (exclusive pricing at Fullscript) or (Amazon)

- Allimed/Allimax Pro: (exclusive pricing at Fullscript), or (Amazon)

- Charcoal: (Fullscript) or (Amazon)

- Digestive enzymes: (mentioned 'Pancreatic enzymes' are often prescription: Creon, Zenpep...)

- Ox Bile (exclusive pricing at Fullscript)
 
TESTS MENTIONED:
- Cortisol saliva TEST: "Adrenal Function Profile"
- IBS-Smart TEST

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1/15/2026

Recommendation for Mixed IBS?

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Key Discussions:
  • Introduction to Mixed IBS:
    Mixed IBS is characterized by a combination of diarrhea and constipation symptoms.
  • Testing for SIBO:
    The importance of testing for Small Intestinal Bacterial Overgrowth (SIBO) is highlighted as a first step in diagnosing and managing Mixed IBS. Confirm SIBO before proceeding with SIBO treatment.
  • Symptomatic Relief:
    While waiting for test results and determining the underlying cause, symptomatic relief treatments can be used. See siboinfo: symptom relief page, which offer strategies for managing both diarrhea and constipation.
  • Probiotics and Fiber:
    The use of probiotics and certain types of fiber, such as partially hydrolyzed guar gum, is recommended for those who can tolerate them. Start with small amounts and gradually increase to label dose over a week.
  • Further Testing:
    If SIBO is ruled out, additional tests such as blood work and stool tests are suggested to further investigate the cause of symptoms.
Takeaways:
  • Step-by-Step Approach: Begin with testing for SIBO and proceed with treatment based on results.
  • Symptom Management: for immediate relief 
  • Gradual Introduction: When trying new supplements like fiber, introduce them slowly to monitor tolerance.
  • Comprehensive Testing: Consider further diagnostic tests if initial results are inconclusive.

Products mentioned:
– Symptomatic Relief Supplements (exclusive pricing at Fullscript)
– Probiotics (exclusive pricing at Fullscript)
– Fiber/PHGG: (exclusive pricing at Fullscript), or (Amazon: Healthy Fiber)


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1/8/2026

When to Start Prokinetics for SIBO? Are They Taken with Antibiotics

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Highlights:
  • Prokinetics timing and use for SIBO Prevention:
    • Prokinetics are used between treatment rounds to prevent relapse, which is common around two weeks after treatment.
  • SIBO Management:
    • Recommendations on the use of low-dose naltrexone (LDN) and its gradual titration to manage side effects
    • Insights into whether continuing prokinetics during treatment rounds affects outcome
    • Discussion on the financial aspect of continuing medication during treatment rounds.
Key Takeaways:
  • Prokinetics are often used as a preventive measure against relapse in SIBO treatment.
  • Retesting is crucial to determine the necessity of continued medication.
  • LDN is recommended to be continued due to its gradual titration and potential side effects.
  • The decision to continue prokinetics during treatment should consider both clinical outcomes and cost implications.
Conclusions:
  • Prokinetics are taken between SIBO treatment rounds and also after SIBO is eradicated for prevention of relapse.
  • Once started, prokinetics can be continued during the next antibacterial treatment round, but it's not necessary.
  • Due to needing to titrate LDN up, it is typically continued during antibacterial rounds, once started.

Products mentioned:
– LDN (low dose Naltrexone - Rx)
– Herbal prokinetic options (exclusive pricing at Fullscript)


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1/1/2026

Negative SIBO Test After Treatment, But Symptoms Got Worse?

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Key Discussions:
  1. Treatment Journey with Xifaxan:
    The clip begins with a discussion about a personal experience with treating hydrogen SIBO using Xifaxan. The patient underwent four rounds of treatment, noting improvement in symptoms like bloating and gas after the initial rounds, but a worsening of symptoms after the third and fourth rounds.
  2. Testing and Symptoms:
    Despite testing negative for SIBO after the fourth round, symptoms worsened, leading to confusion about the test results and their implications.
  3. Potential Causes and Testing:
    The conversation explores possible reasons for the negative test results despite ongoing symptoms. False negative tests results and their causes are discussed, such as unusual diarrhea close to the test, or hydrogen sulfide SIBO that wasn't detected.
  4. Exploring Other Conditions:
    The discussion expands to consider other potential conditions that might be causing the symptoms, such as yeast overgrowth or parasites, and the importance of a differential diagnosis.
  5. Diagnostic Approaches:
    Dr. Allison Siebecker emphasizes the need for comprehensive testing, including stool tests, to rule out other conditions and to better understand the underlying issues.
Conclusion:
This discusses why symptoms may persist after a negative SIBO test, including false negative test results and other potential health issues.

Products Mentioned:
- Trio-Smart SIBO test (tests all 3 gases: hydrogen sulfide - plus methane and hydrogen).
Note: sample every 22 minutes to stretch the test to ~ 3 hours.

- Stool and SIBO tests
Note: these labs offer direct ordering for patients and non-prescribing practitioners of SIBO and various stool and other tests.
- Rupa Health
- Direct Labs
- 
True Health 

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  • HOME
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