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1/1/2026

Negative SIBO Test After Treatment, But Symptoms Got Worse?

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Key Discussions:
  1. Treatment Journey with Xifaxan:
    The clip begins with a discussion about a personal experience with treating hydrogen SIBO using Xifaxan. The patient underwent four rounds of treatment, noting improvement in symptoms like bloating and gas after the initial rounds, but a worsening of symptoms after the third and fourth rounds.
  2. Testing and Symptoms:
    Despite testing negative for SIBO after the fourth round, symptoms worsened, leading to confusion about the test results and their implications.
  3. Potential Causes and Testing:
    The conversation explores possible reasons for the negative test results despite ongoing symptoms. False negative tests results and their causes are discussed, such as unusual diarrhea close to the test, or hydrogen sulfide SIBO that wasn't detected.
  4. Exploring Other Conditions:
    The discussion expands to consider other potential conditions that might be causing the symptoms, such as yeast overgrowth or parasites, and the importance of a differential diagnosis.
  5. Diagnostic Approaches:
    Dr. Allison Siebecker emphasizes the need for comprehensive testing, including stool tests, to rule out other conditions and to better understand the underlying issues.
Conclusion:
This discusses why symptoms may persist after a negative SIBO test, including false negative test results and other potential health issues.

Products Mentioned:
- Trio-Smart SIBO test (tests all 3 gases: hydrogen sulfide - plus methane and hydrogen).
Note: sample every 22 minutes to stretch the test to ~ 3 hours.

- Stool and SIBO tests
Note: these labs offer direct ordering for patients and non-prescribing practitioners of SIBO and various stool and other tests.
- Rupa Health
- Direct Labs
- 
True Health 

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  • HOME
    • HOME
  • About SIBO
    • WHAT IS SIBO?
    • SIBO Symptoms
    • Associated Diseases
    • What Causes SIBO?
    • SIBO & IBS
  • SIBO TESTS
    • SIBO Tests
  • TREATMENT
    • How To Treat SIBO
    • Symptom Relief
    • What to Avoid
    • Antibiotics
    • Herbal Antibiotics
    • Elemental Diet
    • SIBO Diet
    • Prevention of Relapse
    • Probiotics
  • SIBO COURSES
    • SIBO Courses
  • SIBO SUPPORT
    • SIBO Support
  • RESOURCES
    • Discounts
    • BLOG
    • SIBO Podcasts
    • SIBO Studies >
      • SIBO Studies: 2025
      • SIBO Studies: 2024
      • SIBO Studies: 2023
      • SIBO Studies: 2022
      • SIBO Studies: 2021
      • SIBO Studies: 2020
      • SIBO Studies: 2019
      • SIBO Studies: 2018
      • SIBO Studies: 2017
      • SIBO Studies: 2016
      • SIBO Studies: 2015
      • SIBO Studies: 2014
      • SIBO Studies: 2013
      • SIBO Studies: 2012
      • SIBO Studies: 2011
      • SIBO Studies: 2009
      • SIBO Studies: 1990's
      • SIBO Studies: 1980's
    • SIBO Books
    • SIBO Recipes & Cookbooks
    • MMC Videos
    • Test Directory
    • Finding a SIBO Doctor
  • CONTACT
    • Contact
    • About Dr. Siebecker
    • Online Consultations
  • Log in button LOGIN