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2/19/2026

Q&A: How To Treat High Levels of Methane SIBO (IMO)?

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This video addresses patient's concern regarding treatment options for high methane SIBO after initial attempts with Xifaxan (Rifaximin) and Neomycin were unsuccessful.
Key Discussion Points:
  • Initial Treatment Assessment:
    • It's noted that rifaximin alone may not be sufficient, as combination therapy is typically required for effective eradication.
    • The patient is understood to have effectively undergone only one round of necessary treatment, and more rounds are likely needed.
  • Addressing "Very High" SIBO:
    • Cases with "very high" readings often require a more intensive approach.
    • Typically, four rounds of - two-week antibiotic treatments (like rifaximin and another agent) are recommended, or four weeks of herbal treatment.
  • Recommended Next Treatment Options:
    • Antibiotic Combination: The suggestion is to begin a second round of treatment, potentially using rifaximin in combination with metronidazole. This is recommended as the patient previously used rifaximin and neomycin.
    • Herbal Alternatives: An alternative is to transition to herbal treatments. This would involve combining one of the following with Allimed (also known as Allimax Pro) or Atrantil:
      • Berberine
      • Oregano
      • Neem
  • Importance of Retesting:
    • Given the likelihood of needing multiple treatment rounds, retesting is crucial to monitor progress and determine the effectiveness of the chosen therapy.
    • It is advised to compare test results consistently (e.g., using the same type of breath test, like the lactulose breath test) to accurately track changes, especially if a doctor is not facilitating necessary retests.
Products mentioned:
~ Antibiotics: Rifaximin (Xifaxan), Neomycin, Metronidazole (Flagyl)

~ Berberine: https://us.fullscript.com/plans/asiebecker-herbal-antibiotics-for-sibo (discounted at Fullscript), https://amzn.to/4a6pmEI (Amazon)

~ Oregano "ADP": https://us.fullscript.com/plans/asiebecker-herbal-antibiotics-for-sibo (discounted at Fullscript), https://amzn.to/3T94BSO (Amazon)

~ Neem: https://us.fullscript.com/plans/asiebecker-herbal-antibiotics-for-sibo (discounted at Fullscript), https://amzn.to/3RaPPIH (Amazon)

~ Allicin - Allimed/Allimax Pro: https://us.fullscript.com/plans/asiebecker-herbal-antibiotics-for-sibo (discounted at Fullscript), https://amzn.to/3Tg4bdb (Amazon)

~ Atrantil: https://us.fullscript.com/plans/asiebecker-herbal-antibiotics-for-sibo (discounted at Fullscript), https://amzn.to/3Gwd8Yh (Amazon)

~ FoodMarble SIBO test: https://foodmarble.com/shop?discount_code=SAVE16 (16% off Foodmarble at checkout)

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  • HOME
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  • About SIBO
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    • SIBO Symptoms
    • Associated Diseases
    • What Causes SIBO?
    • SIBO & IBS
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    • SIBO Tests
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    • Symptom Relief
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    • Antibiotics
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    • Elemental Diet
    • SIBO Diet
    • Prevention of Relapse
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