2018 Research Articles
Overview
Underlying Causes (pathophysiological)
Pathophysiology
Causes/Risk Factors
Antibiotics Diseases
PPI's/Hypochlorhydria
Surgery
Associated Conditions
Amyloidosis New Childhood Stunted Growth New
Testing
Methane
Hydrogen Sulfide
Treatment
Antibiotics: Rifaximin
Probiotics
Prokinetics
FMT
Diet
Diet: Low FODMAP Diet
- Small Intestinal Bacterial Overgrowth: Nutritional Implications, Diagnosis, and Management. PMID: 29413012
Underlying Causes (pathophysiological)
- Vagal dysfunction and small intestinal bacterial overgrowth: novel pathways to chronic inflammation in HIV. PMID: 29596112
Pathophysiology
- Characterization of Small Intestine Microbiotia in Patients Undergoing Evaluation for Suspected SIBO
- A SUBSET OF SYMPTOMATIC PATIENTS EXHIBIT SMALL INTESTINAL DYSBIOSIS IRRESPECTIVE OF QUANTITATIVE DUODENAL ASPIRATE CULTURE RESULTS.
- Neither Serum Vitamin B12 nor Methylmalonic Acid Values are Reliable Markers of Vitamin B12 Sufficiency in Children with Short Bowel Syndrome
- ANTIBODIES TO CAMPYLOBACTER JEJUNI-DERIVED CYTOLETHAL DISTENDING TOXIN B AND HUMAN VINCULIN LOCALIZE TO THE GASTROINTESTINAL TRACT AFTER IN VIVO ACUTE ADMINISTRATION
- Abdominal distension in health and irritable bowel syndrome: The effect of bladder filling. PMID: 30070066
Causes/Risk Factors
Antibiotics Diseases
- Microbiome-Gut-Brain Axis and Toll-Like Receptors in Parkinson's Disease. PMID: 29882798
- ANTIBODIES TO CAMPYLOBACTER JEJUNI-DERIVED CYTOLETHAL DISTENDING TOXIN B AND HUMAN VINCULIN LOCALIZE TO THE GASTROINTESTINAL TRACT AFTER IN VIVO ACUTE ADMINISTRATION
PPI's/Hypochlorhydria
- Intestinal Dysbiosis Secondary to Proton-Pump Inhibitor Use. PMID: 29316555
- Is It Useful to Administer Probiotics Together With Proton Pump Inhibitors in Children With Gastroesophageal Reflux? PMID: 29291607
- Risk of small intestinal bacterial overgrowth in patients receiving proton pump inhibitors versus proton pump inhibitors plus prokinetics: Small intestinal bacterial overgrowth. DOI: 10.1002/jgh3.12045
- Bowel symptoms in patients that receive proton pump inhibitors. Results of a multicenter survey in Mexico. PMID: 29678362
- Proton Pump Inhibitors: Risks and Rewards and Emerging Consequences to the Gut Microbiome. PMID: 30071147
Surgery
- Cirrhosis following single anastomosis duodeno-ileal switch: A case report. PMID: 29605778
- Chronic diarrhoea following surgery for colon cancer-frequency, causes and treatment options. PMID: 29589108
- The gut-liver axis: impact of a mouse model of small-bowel bacterial overgrowth. PMID: 29229136
- Resolution of late-onset heart and liver failures after reversion of jejuno-ileal bypass: a case report. PMID: 29790800
- Does colectomy predispose to small intestinal bacterial (SIBO) and fungal overgrowth (SIFO)? PMID: 29691369
- Bacteria, Bones, and Stones: Managing Complications of Short Bowel Syndrome. PMID: 29926935
- Intestinal manipulation affects mucosal antimicrobial defense in a mouse model of postoperative ileus. PMID: 29652914
- Small intestinal bacterial overgrowth (SIBO) and vitamin K-responsive coagulopathy: a previously unrecorded association. PMID: 29880619
- SIBO: Clinical Presentation in Patients with Roux-En-Y Gastric Bypass
- Small intestinal bacterial overgrowth is common after gastrectomy but with little impact on nutritional status. PMID: 30197248
Associated Conditions
Amyloidosis New Childhood Stunted Growth New
- Stunted childhood growth is associated with decompartmentalization of the gastrointestinal tract and overgrowth of oropharyngeal taxa. PMID: 30126990
- Early Life Interventions for Childhood Growth and Development in Tanzania (ELICIT): a protocol for a randomized factorial, double-blind, placebo-controlled trial of azithromycin, nitazoxanide and nicotinamide. PMID: 29982218
- Pathophysiology, Diagnosis, and Management of Chronic Intestinal Pseudo-Obstruction. PMID: 29877952
- SEVERE GASTROINTESTINAL DYSMOTILITY RELATED INTESTINAL FAILURE: CHRONIC INTESTINAL PSEUDO-OBSTRUCTION, ENTERIC DYSMOTILITY OR A ‘PRAGMATIC’ APPROACH? EXPERIENCE FROM A UK NATIONAL REFERRAL CENTRE
- Small Intestinal Bacterial Overgrowth and Coronary Artery Disease: What Is in the CArDs? PMID: 29307000
- The role of small intestinal bacterial overgrowth in cystic fibrosis: a randomized case-controlled clinical trial with rifaximin. PMID: 30232597
- Brain fogginess, gas and bloating: a link between SIBO, probiotics and metabolic acidosis. PMID: 29915215
- Brain Fogginess and SIBO: A Link or Just a Mirage? PMID: 30237404
- The characteristics of small intestinal bacterial overgrowth in patients with gallstone diseases. PMID: 29392773
- Vagal dysfunction and small intestinal bacterial overgrowth: novel pathways to chronic inflammation in HIV. PMID: 29596112
- Testing and Treating Small Intestinal Bacterial Overgrowth Reduces Symptoms in Patients with Inflammatory Bowel Disease. PMID: 29761252
- Serum Unconjugated Bile Acids and Small Bowel Bacterial Overgrowth in Pediatric Intestinal Failure: A Pilot Study. PMID: 30035316
- The gut microbiome and irritable bowel syndrome: State of art review. PMID: 29935865
- Prevalence and predictors of small intestinal bacterial overgrowth in irritable bowel syndrome: a systematic review and meta-analysis. PMID: 29761234
- Evaluation of chronic diarrhea and irritable bowel syndrome with diarrhea in adults in the era of precision medicine. PMID: 29713027
- Rome Foundation Working Team Report on Post-Infection Irritable Bowel Syndrome. PMID: 30009817
- Fecal Microbiota Alterations Associated With Diarrhea-Predominant Irritable Bowel Syndrome. PMID: 30090090
- The role of intestinal microbiota in the pathogenesis of NAFLD: starting points for intervention. PMID: 2976546
- Pattern of Hydrogen and Methane Production by Gut Microbiome in Non-Alcoholic Disease (NAFLD): A Large-Scale Matched Case-Control Study
- Bile Acid-Induced Activation of ERK/Sphingosine Kinase 2 contributes to Intestinal Inflammation and Barrier Dysfunction in Multi-Drug Resistance 2 Gene Deficient Mice
- The Prevalence of SIBO in Adults with Non-alcoholic Fatty Liver Disease
- Resolution of late-onset heart and liver failures after reversion of jejuno-ileal bypass: a case report. PMID: 29790800
- Clinical impact of microbiome in patients with decompensated cirrhosis. PMID: 30228776
- Kleine-Levin syndrome: the contribution of PET scan and hydrogen breath test for small intestinal bacterial overgrowth. PMID: 29773218
- The prevalence of small intestinal bacterial overgrowth in non-surgical patients with chronic pancreatitis and pancreatic exocrine insufficiency (PEI). PMID: 29502987
- Small intestine bacterial overgrowth in chronic pancreatitis. DOI: 10.25121/PNM.2017.30.11.619
- Chronic pancreatitis and small intestinal bacterial overgrowth. PMID: 29752215
- Diagnosis and Management of Exocrine Pancreatic Insufficiency. PMID: 30027527
- Small intestinal bacterial overgrowth in Parkinson's disease: Tribulations of a trial. PMID: 29636215
- Microbiome-Gut-Brain Axis and Toll-Like Receptors in Parkinson's Disease. PMID: 29882798
- Weight Loss in Parkinson's Disease: No Evidence for Role of Small Intestinal Bacterial Overgrowth. PMID: 30149465
- Successful treatment of postural orthostatic tachycardia and mast cell activation syndromes using naltrexone, immunoglobulin and antibiotic treatment. PMID: 9326369
- The gastrointestinal symptoms present in patients with postural tachycardia syndrome: A review of the literature and overview of treatment. https://doi.org/10.1016/j.autneu.2018.09.003
- Oral psoriasis and sibo: is there a link? PMID: 29575224
- The association between cigarettes smoke, small intestine bacterial overgrowth and rosacea. PMID: 29485256
- Bacteria, Bones, and Stones: Managing Complications of Short Bowel Syndrome. PMID: 29926935
- Starch Tolerance and the Short Bowel. PMID: 29762383
- Neither Serum Vitamin B12 nor Methylmalonic Acid Values are Reliable Markers of Vitamin B12 Sufficiency in Children with Short Bowel Syndrome
- Remnant Small Bowel Length in Pediatric Short Bowel Syndrome and the Correlation with Intestinal Dysbiosis and Linear Growth. PMID: 30077861
- [Thyroid dysfunction in patients with small intestinal bacterial overgrowth]. Polish. PMID: 29374417
- Small intestinal bacterial overgrowth (SIBO) and vitamin K-responsive coagulopathy: a previously unrecorded association. PMID: 29880619
Testing
- The North American Consensus on Breath Testing: The Controversial Diagnostic Role of Lactulose in SIBO. PMID: 29535443
- Does a glucose-based hydrogen and methane breath test detect bacterial overgrowth in the jejunum? PMID: 29687525
- Case of small intestinal bacterial overgrowth carried out by capsule and double-balloon endoscopy. PMID: 29729056
- Investigation of SIBO in Diabetics Using Fructose Breath Test
- Does Bowel Preparation Affect Duodenal Aspirate Culture for SIBO?
- Comparative Quantitative Analysis Between the North American Consensus Positive Hydrogen Breath Test- SIBO Versus Traditional Thresholds
- The Convergence of Bacterial Overgrowth, Systemic Inflammatory Biomarkers, and Anti-Vinculin Antibodies in Determining the Response to Rifaximin Treatment in Diarrheal-Predominant IBS Subjects
- ANTIBODIES TO CAMPYLOBACTER JEJUNI-DERIVED CYTOLETHAL DISTENDING TOXIN B AND HUMAN VINCULIN LOCALIZE TO THE GASTROINTESTINAL TRACT AFTER IN VIVO ACUTE ADMINISTRATION
- Validation of a 4-Gas Device for Breath Testing in the Determination of Small Intestinal Bacterial Overgrowth
- The safety and sensitivity of a telemetric capsule to monitor gastrointestinal hydrogen production in vivo in healthy subjects: a pilot trial comparison to concurrent breath analysis. PMID: 30067289
- Serum Unconjugated Bile Acids and Small Bowel Bacterial Overgrowth in Pediatric Intestinal Failure: A Pilot Study. PMID: 30035316
- NON-INVASIVE DIAGNOSIS OF IRRITABLE BOWEL SYNDROME VIA NOVEL BOWEL SOUND FEATURES: PROOF OF PRINCIPLE
- Neither Serum Vitamin B12 nor Methylmalonic Acid Values are Reliable Markers of Vitamin B12 Sufficiency in Children with Short Bowel Syndrome
Methane
- Effect of Bifidobacterium infantis 35624 (Align) on the Lactulose Breath Test for Small Intestinal Bacterial Overgrowth. PMID: 29397491
- Elevated methane levels in small intestinal bacterial overgrowth suggests delayed small bowel and colonic transit. PMID: 29794732
- Competitive Hydrogen Gas Utilization by Methane – and Hydrogen Sulfide-Producing Microorganisms and Associated Symptoms: Results of a Novel 4-Gas Breath Testing Machine
- Breath methane concentrations and markers of obesity in patients with functional gastrointestinal disorders. PMID: 29881615
- IMPROVEMENTS IN METABOLIC PARAMETERS IN PRE-DIABETIC SUBJECTS WITH OBESITY FOLLOWING METHANE ERADICATION IS ASSOCIATED WITH REDUCTION IN METHANOGENS AND CHANGES IN GUT MICROBIAL POPULATIONS
- ERADICATION OF BREATH METHANE USING ANTIBIOTICS RESULTS IN CHANGES IN SHORT CHAIN FATTY ACID LEVELS IN PREDIABETIC SUBJECTS WITH OBESITY
- PREVALENCE OF METHANOGENS AND ASSOCIATED FACTORS IN PATIENTS WITH IRRITABLE BOWEL SYNDROME (IBS) AND HEALTHY CONTROLS IN A MEXICAN POPULATION
Hydrogen Sulfide
- Hydrogen sulfide in physiology and pathogenesis of bacteria and viruses. PMID: 29601123
- Breath Hydrogen Sulfide Does Not Correlate With Constipation
- A Novel 4-Gas Device for Breath Testing Shows Exhaled H2S is Associated with Diarrhea and Abdominal Pain in a Large Scale Prospective Trial
- Validation of a 4-Gas Device for Breath Testing in the Determination of Small Intestinal Bacterial Overgrowth
- Competitive Hydrogen Gas Utilization by Methane – and Hydrogen Sulfide-Producing Microorganisms and Associated Symptoms: Results of a Novel 4-Gas Breath Testing Machine
- Presence of Hydrogen Consumptive Microbes Increases Peak of Hydrogen Concentration
- DIETARY EMULSIFIER POLYSORBATE-80 INCREASES THE PROTEUS GENUS AND EXACERBATES INTESTINAL INFLAMMATION ON INDMETHACIN-INDUCED ILEITIS
Treatment
- New treatments and therapeutic targets for IBS and other functional bowel disorders. PMID: 29930260
- Naturopathic Approaches to Irritable Bowel Syndrome—A Delphi Study. http://doi.org/10.1089/acm.2018.0255
- Efficacy of glutamine in postinfection IBS. PMID: 30244201
Antibiotics: Rifaximin
- Status of Rifaximin: A Review of Characteristics, Uses and Analytical Methods. PMID: 29580065
- Gut Microbiota-Based Therapies for Irritable Bowel Syndrome. PMID: 29446765
- Evidence-based management of irritable bowel syndrome with diarrhea. PMID: 29372991
- Pharmacokinetic drug evaluation of rifaximin for treatment of diarrhea-predominant irritable bowel syndrome. PMID: 29897844
- New concepts on intestinal microbiota and the role of the non-absorbable antibiotics with special reference to in digestive diseases. PMID: 29807873
- Effects of on Central Responses to Social Stress-a Pilot Experiment. PMID: 29713909
- Rifaxmin is associated with modest, transient decreases in multiple taxa in the gut microbiota of patients with diarrhoea-predominant irritable bowel syndrome. PMID: 29708822
- Reduces Markers of Inflammation and Bacterial 16S rRNA in Zambian Adults with Hepatosplenic Schistosomiasis: A Randomized Control Trial. PMID: 29436337
- Lack of Development of Opportunistic Infections, Including Candidiasis, in Patients with Diarrhea-Predominant IBS Receiving Repeat Treatment with Rifaximin
- CHARACTERIZATION OF LONG-TERM RIFAXIMIN RESPONDERS FROM A PHASE 3, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED REPEAT TREATMENT TRIAL FOR DIARRHEA-PREDOMINANT IRRITABLE BOWEL SYNDROME (IBS-D)
- EFFICACY OF RIFAXIMIN ON BLOATING IN PATIENTS WITH DIARRHEA–PREDOMINANT IRRITABLE BOWEL SYNDROME (IBS–D): A POOLED ANALYSIS OF THREE PHASE 3, RANDOMIZED, PLACEBO–CONTROLLED TRIALS
- EFFICACY OF RIFAXIMIN IN PATIENTS WITH DIARRHEA-PREDOMINANT IRRITABLE BOWEL SYNDROME (IBS-D) AND PRIOR USE OF IBS MEDICATIONS
- Rifaximin Repeat Treatment for Diarrhea-Predominant IBS and Impact on Clostridium Difficile Infection Development
- Review article: an analysis of safety profiles of the treatments for diarrhoea-predominant irritable bowel syndrome. PMID: 30194692
- The role of small intestinal bacterial overgrowth in cystic fibrosis: a randomized case-controlled clinical trial with rifaximin. PMID: 30232597
- Fecal Microbiota Alterations Associated With Diarrhea-Predominant Irritable Bowel Syndrome. PMID: 30090090
- The role of small intestinal bacterial overgrowth in cystic fibrosis: a randomized case-controlled clinical trial with rifaximin. PMID: 30232597
- No effect of rifaximin on soluble CD163, mannose receptor or type III and IV neoepitope collagen markers in decompensated cirrhosis: Results from a randomized, placebo controlled trial. PMID: 30183743
- Rifaximin anti-inflammatory activity on bovine endometrium primary cell cultures: a preliminary study. PMID: 29984902
Probiotics
- Effect of a Preparation of Four Probiotics on Symptoms of Patients with Irritable Bowel Syndrome: Association with Intestinal Bacterial Overgrowth. PMID: 29508268
- Effect of Bifidobacterium infantis 35624 (Align) on the Lactulose Breath Test for Small Intestinal Bacterial Overgrowth. PMID: 29397491
- Aciduric Strains of Lactobacillus reuteri and Lactobacillus rhamnosus, Isolated from Human Feces, Have Strong Adhesion and Aggregation Properties. PMID: 8756502
- Is It Useful to Administer Probiotics Together With Proton Pump Inhibitors in Children With Gastroesophageal Reflux? PMID: 29291607
- A randomized placebo-controlled clinical trial of a multi-strain probiotic formulation (Bio-Kult®) in the management of diarrhea-predominant irritable bowel syndrome. PMID: 29801486
Prokinetics
- Manometric evaluation of the motilin receptor agonist camicinal (GSK962040) in humans. PMID: 28782145
- Nonclinical Cardiovascular Studies of Prucalopride, a Highly Selective 5-Hydroxytryptamine 4 Receptor Agonist. PMID: 29180358
- Risk of small intestinal bacterial overgrowth in patients receiving proton pump inhibitors versus proton pump inhibitors plus prokinetics: Small intestinal bacterial overgrowth. DOI: 10.1002/jgh3.12045
FMT
Diet
- Use of Dietary Management in Irritable Bowel Syndrome: Results of a Survey of over 1500 United States Gastroenterologists. PMID: 29886578
- EXCLUSION DIETS AND IRRITABLE BOWEL SYMPTOMS: A SYSTEMATIC REVIEW AND META-ANALYSIS
Diet: Low FODMAP Diet
- Low-FODMAP vs regular rye bread in irritable bowel syndrome: Randomized SmartPill™ study. PMID: 29568206
- Low FODMAP Diet for IBS. PMID: 29526727
- Adherence to a Low FODMAP Diet in Relation to Symptoms of Irritable Bowel Syndrome in Iranian Adults. PMID: 29497906
- Fermentable short chain carbohydrate (FODMAP) content of common plant-based foods and processed foods suitable for vegetarian- and vegan-based eating patterns. 29473657
- Radiation-induced enteropathy - how a low-FODMAP diet might help. PMID: 29433349
- The low FODMAP diet in the management of irritable bowel syndrome: an evidence-based review of FODMAP restriction, reintroduction and personalisation in clinical practice. PMID: 29336079
- Letter: irritable bowel syndrome-how a low-FODMAP diet or yoga might help. PMID: 29314135
- Letter: irritable bowel syndrome-how a low-FODMAP diet or yoga might help. Authors' reply. PMID: 29314128
- Exploring Gut Microbiota Composition as an Indicator of Clinical Response to Dietary FODMAP Restriction in Patients with Irritable Bowel Syndrome. PMID: 29302878
- FODMAP diet modulates visceral nociception by lipopolysaccharide-mediated intestinal inflammation and barrier dysfunction. PMID: 29202473
- Effects of Prebiotics vs a Diet Low in Fodmaps in Patients with Functional Gut Disorder. PMID: 29964041
- COOL Use of Sourdough in Low FODMAP Baking. PMID: 29932101
- Dietary Fermentable Oligosaccharides, Disaccharides, Monosaccharides, and Polyols (FODMAPs) and Gastrointestinal Disease. PMID: 29870082
- [Diet low in fermentable oligosaccharides, disaccharides, monosaccharides and polyols, and quality of life in patients with irritable bowel syndrome in Colombia]. PMID: 29809329
- The role of diet in the management of irritable bowel syndrome: a focus on FODMAPs. PMID: 29764234
- Applying a Low-FODMAP Dietary Intervention to a Female Ultra-Endurance Runner With Irritable Bowel Syndrome During a Multi-Stage Ultra-Marathon. PMID: 29757053
- Evaluation of FODMAP Carbohydrates Content in Selected Foods in the United States. PMID: 29706489
- A Pilot Study of the Effect of Green Kiwifruit on Human Intestinal Fermentation Measured by Hydrogen and Methane Breath Testing. PMID: 29694795
- [Implementationof a low FODMAP dietforfunctional abdominal pain]. PMID: 29685830
- Low fermentable oligo-di-mono-saccharides and polyols diet versus general dietary advice in patients with diarrhea-predominant irritable bowel syndrome: A randomized controlled trial. PMID: 29159993
- AN ADAPTED LOW FODMAP DIET IS SAFE AND EFFECTIVE ALSO IN THE LONG TERM
- THE IMPACT OF HIGH VS. LOW FODMAP DIET ON GI SYMPTOMS AND BREATH HYDROGEN & METHANE EXCRETION IN THAI HEALTHY VOLUNTEERS AND SUBJECTS WITH FUNCTIONAL BLOATING
- REDUCING FODMAP CONTENT IN THE BREASTFEEDING MOTHER’S DIET ALLEVIATES THE SYMPTOMS OF INFANTILE COLIC: A RANDOMISED CONTROLLED DOUBLE-BLIND CROSSOVER FEEDING STUDY
- GUT MICROBIOTA-DIET INTERACTIONS IN A HUMANIZED MOUSE MODEL OF IBS: THE ROLE OF INTESTINAL MAST CELLS
- GUT MICROBIOTA DEFINES HOST RESPONSES TO DIETARY FERMENTABLE CARBOHYDRATES IN IBS: THE ROLE OF BACTERIAL HISTAMINE
- Clinical application of dietary therapies in irritable bowel syndrome. PMID: 30240475
- Applicability of Yeast Fermentation to Reduce Fructans and Other FODMAPs. PMID: 30200589
- The Role of a Low Fermentable Oligosaccharides, Disaccharides, Monosaccharides, and Polyol Diet in Nonceliac Gluten Sensitivity. PMID: 30158962
- Outcome of hospital outpatient treatment of functional gastrointestinal disorders. PMID: 30091176
- Is a low FODMAP diet dangerous? PMID: 30083779
- A low FODMAP diet is associated with changes in the microbiota and reduction in breath hydrogen but not colonic volume in healthy subjects. PMID: 30048547
- A Systematic Review and Meta-Analysis Evaluating the Efficacy of a Gluten-Free Diet and a Low FODMAPs Diet in Treating Symptoms of Irritable Bowel Syndrome. PMID: 30046155
- Use of Dietary Management in Irritable Bowel Syndrome: Results of a Survey of Over 1500 United States Gastroenterologists. PMID: 29886578
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