SIBO - Small Intestinal Bacterial Overgrowth
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2021 Research Articles

​Related
  • Age and the aging process significantly alter the small bowel microbiome.  PMID: 34592155

Overview
  • Other Diseases of the Small Intestine and Colon.  DOI 10.1016/B978-0-323-67293-1.00049-9
  • Small Intestinal Bacterial Overgrowth  PMID: 34024452
  • Small Intestinal Bacterial Overgrowth.  PMID: 31536241 
    
Pathophysiology
  • The role of intraepithelial lymphocytes in pathogenesis of small intestinal bacterial overgrowth syndrome].  PMID: 33713088 
  • A LOWER RISK FOR VITAMIN B12 DEFICIENCY DISTINGUISHES SMALL INTESTINAL BACTERIAL OVERGROWTH (SIBO) CAUSED BY METHANE-PRODUCING ARCHAEA FROM SIBO CAUSED BY HYDROGEN-PRODUCING BACTERIA  doi: 10.1016/S0016-5085(21)01603-6
  • Serotonin Pathway of Tryptophan Metabolism in Small Intestinal Bacterial Overgrowth-A Pilot Study with Patients Diagnosed with Lactulose Hydrogen Breath Test and Treated with Rifaximin  PMID: 34065903
  • THE FIRST SYSTEMS BIOLOGY APPROACH TO THE MICROBIOME OF SIBO BY HIGH-LEVEL CO-OCCURRENCE COMMUNITY NETWORK ANALYSES IDENTIFIES TWO DISTINCT PROTEOBACTERIA-RELATED CLUSTERS  DOI:10.1016/S0016-5085(21)01386-X
  • TRANSPLANTATION OF FUSOBACTERIUM VARIUM IN VIVO RESULTS IN AN INCREASE OF PRO-INFLAMMATORY CYTOKINES AND STOOL WET WEIGHT  DOI:10.1016/S0016-5085(21)02071-0​  Commentary: Hydrogen sulfide bacteria fusobacterium varium: On twitter, Dr. Pimentel commented: “Could this be the culprit in IBS contributing to diarrhea and a positive H2S on new 4 gas breath test? Stay tuned.”
  • Mucosa-Associated Microbial Profile Is Altered in Small Intestinal Bacterial Overgrowth  PMID: 34421869 
  • Quantitative sequencing clarifies the role of disruptor taxa, oral microbiota, and strict anaerobes in the human small-intestine microbiome  PMID: 34724979  “Our findings support a strong relationship between overgrowth of specific disruptor taxa and GI symptoms in subjects with SIBO. High total microbial load alone in the small intestine, was not associated with GI symptoms usually observed in subjects with SIBO and other GI conditions and diseases.”

Causes/Risk Factors
Diseases
  • [Diverticula in the gastrointestinal tract].  PMID: 33560449
  • Association of Presenting Symptoms With Abnormal Laboratory Values for Vector-Borne Illness - Experience in an Urban Gastroenterology Practice.  PMID: 33511252 
  • Effects of Proton Pump Inhibitors on the Small Bowel and Stool Microbiomes.  PMID: 33534012 
  • Percutaneous endoscopic gastrojejunostomy in pediatric intestinal pseudo-obstruction  PMID: 33601120
PPI's/Hypochlorhydria
  • PREVALENCE AND ASSOCIATION OF VITAMIN B12 DEFICIENCY AND SMALL INTESTINAL BACTERIAL OVERGROWTH IN PATIENTS TAKING PROTON PUMP INHIBITORS  doi.org/10.1016/S0016-5085(21)02073-4
Short Bowel Syndrome
  • Modified Antimesenteric Tapering Enteroplasty: An Alternative Technique for the Treatment of Dysfunctional Anastomosis in Patients With Short Bowel. PMID: 34397564
  • NeoCHIRP: A model for intestinal rehabilitation in the neonatal intensive care unit.  PMID: 34270133
Small Intestine Obstruction
  • Laparoscopic Management of Congenital Intestinal Obstruction: Duodenal Atresia and Small Bowel Atresia.  PMID: 34357817
  • Structural and quantitative alterations of gut microbiota in experimental small bowel obstruction.  PMID: 34347831
Surgery: Gastrectomy and Roux-en-Y 
  • Gastrectomy impact on the gut microbiome in patients with gastric cancer: A comprehensive review. PMID: 34354801
  • Proximal Gastrectomy Is a Viable Alternative to Total Gastrectomy in Early Stage Proximal Gastric Cancer. PMID: 34483639
  • The Impact of Bariatric Surgery on the Development of Small Intestinal Bacterial Overgrowth (SIBO).  doi:10.1016/j.jamcollsurg.2021.08.028
  • Assessment of the Burden of Small Intestinal Bacterial Overgrowth (SIBO) in Patients After Oesophagogastric (OG) Cancer Resection  PMID: 34671913
Surgery/Injury 
  • Serum Gastrin Predicts Hydrogen-Producing Small Intestinal Bacterial Overgrowth in Patients With Abdominal Surgery: A Prospective Study.  DOI: 10.14309/ctg.0000000000000291
  • Small intestinal bacterial overgrowth in spinal cord injury patients.  PMID: 33640466  

​Associated Conditions
Alzheimer's disease NEW 
  • Small intestinal bacterial overgrowth in Alzheimer's disease  PMID: 34797427
​Cancer
  • Assessment of the Burden of Small Intestinal Bacterial Overgrowth (SIBO) in Patients After Oesophagogastric (OG) Cancer Resection  PMID: 34671913
Children
  • Management of small intestinal bacterial overgrowth by paediatric gastroenterologists in Spain.  PMID: 33371710  
  • Percutaneous endoscopic gastrojejunostomy in pediatric intestinal pseudo-obstruction  PMID: 33601120
  • Management of small intestinal bacterial overgrowth by pediatric gastroenterologists in Spain.  PMID: 33371710
  • An ESPGHAN Position Paper on the Use of Breath Testing in Paediatric Gastroenterology.   PMID: 34292218
  • Laparoscopic Management of Congenital Intestinal Obstruction: Duodenal Atresia and Small Bowel Atresia.  PMID: 3435781
  • ​​NeoCHIRP: A model for intestinal rehabilitation in the neonatal intensive care unit.  PMID: 34270133
  • Association of small intestinal bacterial overgrowth with nonalcoholic fatty liver disease in children: A meta-analysis  PMID: 34855819
  • Small Intestine Bacterial Overgrowth in Bangladeshi Infants Is Associated With Growth Stunting in a Longitudinal Cohort  PMID: 34693912
Chronic diarrhea
  • What Are the Pearls and Pitfalls of the Dietary Management for Chronic Diarrhoea?  PMID: 33919083​
  • Development of a Score to Predict Positive Colonic Histology in Chronic Diarrhea Assessed in Open-access Colonoscopy. PMID: 32833700
Common Variable Immune Disease (CVID) NEW
  • Can concurrent lower gastrointestinal manifestations help the timely diagnosis of small intestinal bacterial overgrowth in CVID patients?  PMID: 32186350  
Diabetes (Gestaional) NEW
  • Application of methane and hydrogen-based breath test in the study of gestational diabetes mellitus and intestinal microbes  PMID: 33932493
Diverticula 
  • [Diverticula in the gastrointestinal tract].  PMID: 33560449 
Dyspepsia 
  • Small Intestinal Bacterial Overgrowth in Functional Dyspepsia: A Systematic Review and Meta-Analysis.  PMID: 33734110 
Fructose Malabsorption
  • Fructose malabsorption: Causes, diagnosis and treatment  PMID: 33818329
 Functional Dyspepsia
  • Changes in oral flora of patients with functional dyspepsia  PMID: 33850203  
  • Concomitant Irritable Bowel Syndrome Does Not Influence the Response to Antimicrobial Therapy in Patients with Functional Dyspepsia  PMID: 34392491
GERD 
  • The prevalence of intestinal dysbiosis in patients referred for antireflux surgery.  PMID: 33475845  
  • PREVALENCE AND ASSOCIATION OF VITAMIN B12 DEFICIENCY AND SMALL INTESTINAL BACTERIAL OVERGROWTH IN PATIENTS TAKING PROTON PUMP INHIBITORS  doi.org/10.1016/S0016-5085(21)02073-4  
Heart Failure 
  • Association of Small Intestinal Bacterial Overgrowth With Heart Failure and Its Prediction for Short-Term Outcomes.  PMID: 33728933  
  • Bacterial metabolites trimethylamine N-oxide and butyrate as surrogates of small intestinal bacterial overgrowth in patients with a recent decompensated heart failure  PMID: 33731747
Hypothyroid  
  • Levothyroxine Sodium Oral Solution Normalizes Thyroid Function in a Patient with Hashimoto's Disease, Gastritis, Diabetic Gastroparesis, and Small Intestinal Bacterial Overgrowth (SIBO).  PMID: 34557042
 IBS
  • Correlation between small intestinal bacterial overgrowth and irritable bowel syndrome and the prognosis of treatment  PMID: 33849121
  • RIFAXIMIN IMPROVES BOTH ABDOMINAL PAIN AND BLOATING IN PATIENTS WITH IRRITABLE BOWEL SYNDROME WITH DIARRHEA: A COMPOSITE ENDPOINT ANALYSIS OF TWO PHASE 3, RANDOMIZED, PLACEBO-CONTROLLED TRIALS  doi.org/10.1016/S0016-5085(21)01398-6
  • RIFAXIMIN SIGNIFICANTLY IMPROVES BOWEL MOVEMENT URGENCY IN PATIENTS WITH IRRITABLE BOWEL SYNDROME WITH DIARRHEA: A POOLED ANALYSIS OF THREE PHASE 3 TRIALS  doi.org/10.1016/S0016-5085(21)01399-8
  • Emerging Role of the Gut Microbiome in Irritable Bowel Syndrome  PMID: 34304786 
  • Uncovering the pathophysiology of irritable bowel syndrome by exploring the gut-brain axis: a narrative review  PMID: 34430628 
  • A Comprehensive Review of Transaminitis and Irritable Bowel Syndrome  PMID: 34322359 
  • Small Intestinal Bacterial Overgrowth In Various Functional Gastrointestinal Disorders: A Case-Control Study  PMID: 34417923 
Inflammatory Bowel Disease
  • Small intestinal bacterial overgrowth and evaluation of intestinal barrier function in patients with ulcerative colitis  PMID: 34306403 
  • Small intestinal bacterial overgrowth in patients with inflammatory bowel disease: A case-control study  PMID: 34390471 
Intestinal Failure 
  • [Mechanism of gut-microbiota-liver axis in the pathogenesis of intestinal failure-associated liver disease].  PMID: 33461259  
  • [Chronic intestinal failure]  PMID: 34264370
Liver Disease 
  • Small intestinal bacterial overgrowth and nonalcoholic fatty liver disease diagnosed by transient elastography and liver biopsy.  PMID: 33406286 
  • Small intestinal bacterial overgrowth and orocecal transit time in patients of nonalcoholic fatty liver disease  PMID: 33867442
  • Leaky Gut and Gut-Liver Axis in Liver Cirrhosis: Clinical Studies Update.  PMID: 33071239
  • Association of small intestinal bacterial overgrowth with nonalcoholic fatty liver disease in children: A meta-analysis  PMID: 34855819
Lyme Disease and Tick Borne Illness 
  • Association of Presenting Symptoms With Abnormal Laboratory Values for Vector-Borne Illness - Experience in an Urban Gastroenterology Practice.  PMID: 33511252  
Pancreatic Disease 
  • Assessment of small intestinal bacterial overgrowth in chronic pancreatitis patients using jejunal aspirate culture and glucose hydrogen breath test.  PMID: 33730978  
  • Intestinal bacterial overgrowth in the early stage of severe acute pancreatitis is associated with acute respiratory distress syndrome  PMID: 33958849
Parkinson’s disease 
  • Response to Comment on "Association of Intestinal Disorders with Parkinson's Disease and Alzheimer's Disease: A Systematic Review and Meta-Analysis".  PMID: 33503369  
  • Association of small intestinal bacterial overgrowth with Parkinson's disease: a systematic review and meta-analysis  PMID: 33863370
  • Evaluation of fecal microbiota transplantation in Parkinson's disease patients with constipation  PMID: 33985520
  • Small Intestinal Bacterial Overgrowth as Potential Therapeutic Target in Parkinson's Disease  PMID: 34769091
Rosacea 
  • Rosacea, Germs, and Bowels: A Review on Gastrointestinal Comorbidities and Gut-Skin Axis of Rosacea.  PMID: 33507499 
  • Dysbiotic gut microbiota in inflammatory rosacea patients: another clue towards the existence of a brain-gut-skin axis  PMID: 33913159
 Short Bowel Syndrome
  • Fecal microbiome alterations in pediatric patients with short bowel syndrome receiving a rotating cycle of gastrointestinal prophylactic antibiotics.  PMID: 34156541
Spinal Cord Injury 
  • Small intestinal bacterial overgrowth in spinal cord injury patients.  PMID: 33640466  
  • Small intestinal bacterial overgrowth in spinal cord injury patients DOI: 10.1016/j.gastre.2021.09.005
Spondylarthropathy NEW
  • High prevalence of small intestinal bacterial overgrowth (SIBO) in spondylarthropathy.  PMID: 33427609  
Systemic Sclerosis 
  • Prevalence and predictors of small intestinal bacterial overgrowth in systemic sclerosis: a systematic review and meta-analysis.  PMID: 33426631  
Thyroid
  • Small Intestinal Bacterial Overgrowth in Subclinical Hypothyroidism of Pregnant Women.  PMID: 34108932

 Testing
  • Every Breath Test You Take: Practical Advice on Breath Testing Used to Detect Small Intestinal Bacterial Overgrowth.  PMID: 33428040 
  • Serum Gastrin Predicts Hydrogen-Producing Small Intestinal Bacterial Overgrowth in Patients With Abdominal Surgery: A Prospective Study.  PMID: 33369565 
  • How the North American Consensus Protocol Affects the Performance of Glucose Breath Testing for Bacterial Overgrowth Versus a Traditional Method.  PMID: 33560649  
  • EXHALED HYDROGEN SULFIDE IS INCREASED IN PATIENTS WITH DIARRHEA- RESULTS OF A NOVEL COLLECTION AND BREATH TESTING DEVICE  DOI:10.1016/S0016-5085(21)01391-3
  • BREATH HYDROGEN RESPONSES MEASURED BY A NOVEL PORTABLE HYDROGEN BREATH ANALYZER AND SMART PHONE APP USED AT HOME CAN DISTINGUISH NORMAL SUBJECTS FROM PATIENTS WITH SUSPECTED SIBO.  Sa384
  • Serotonin Pathway of Tryptophan Metabolism in Small Intestinal Bacterial Overgrowth-A Pilot Study with Patients Diagnosed with Lactulose Hydrogen Breath Test and Treated with Rifaximin  PMID: 34065903
  • Bacterial Overgrowth of the Small Intestine Breath Test  doi.org/10.1016/B978-0-323-43044-9.00009-1
  • Small-bowel aspiration during upper esophagogastroduodenoscopy: Rao technique.  PMID: 33898888
  • Pattern of methane levels with lactulose breath testing; can we shorten the test duration?  PMID: 34263076    
  • ​​Characteristics of oxygen concentration and the role of correction factor in real-time GI breath test  PMID: 34168044
  • A Promising Approach: Artificial Intelligence Applied to Small Intestinal Bacterial Overgrowth (SIBO) Diagnosis Using Cluster Analysis   PMID: 34441379  
  • An ESPGHAN Position Paper on the Use of Breath Testing in Paediatric Gastroenterology.   PMID: 34292218
  • European guideline on indications, performance, and clinical impact of hydrogen and methane breath tests in adult and pediatric patients: European Association for Gastroenterology, Endoscopy and Nutrition, European Society of Neurogastroenterology and Motility, and European Society for Paediatric Gastroenterology Hepatology and Nutrition consensus.  PMID: 34431620

 Methane
  • Methane and fatty acid metabolism pathways are predictive of Low-FODMAP diet efficacy for patients with irritable bowel syndrome.  PMID: 33504454 
  • AN ELEVATION IN METHANE IS ASSOCIATED WITH AN ANTI-INFLAMMATORY CYTOKINE PROFILE SIMILAR TO GLUCOCORTICOIDS  DOI:10.1016/S0016-5085(21)02322-2
  • Pattern of methane levels with lactulose breath testing; can we shorten the test duration?  PMID: 34263076 
  • ​
  • Distinctive Clinical Correlates of Small Intestinal Bacterial Overgrowth with Methanogens  doi:10.1016/j.cgh.2021.09.035
  • Meconial Methanobrevibacter smithii suggests intrauterine methanogen colonization in preterm neonates.  PMID: 34841325 
  • Exhaled Methane is Associated with a Lower Heart Rate.  PMID: 34915468

Hydrogen Sulfide
  • TRANSPLANTATION OF FUSOBACTERIUM VARIUM IN VIVO RESULTS IN AN INCREASE OF PRO-INFLAMMATORY CYTOKINES AND STOOL WET WEIGHT  DOI:10.1016/S0016-5085(21)02071-0
         Commentary: Hydrogen sulfide bacteria fusobacterium varium: On twitter, Dr. Pimentel commented: “Could this
          be the culprit in IBS contributing to diarrhea and a positive H2S on new 4 gas breath test? Stay tuned.”
  • EXHALED HYDROGEN SULFIDE IS INCREASED IN PATIENTS WITH DIARRHEA- RESULTS OF A NOVEL COLLECTION AND BREATH TESTING DEVICE  DOI:10.1016/S0016-5085(21)01391-3
  • [The diagnostic value of hydrogen sulfide breath test for small intestinal bacterial overgrowth]  PMID: 33765706

Treatment
  • Management of small intestinal bacterial overgrowth by paediatric gastroenterologists in Spain.  PMID: 33371710  
  • Efficacy of a curcumin extract (Curcugen™) on gastrointestinal symptoms and intestinal microbiota in adults with self-reported digestive complaints: a randomised, double-blind, placebo-controlled study.  PMID: 33478482 
  • NEW Exploring Mucin as Adjunct to Phage Therapy.  PMID: 33670927
  • Effects of Bovine Colostrum with or without Egg on In Vitro Bacterial-Induced Intestinal Damage with Relevance for SIBO and Infectious Diarrhea  PMID: 33809940  Commentary: This study shows Colostrum, with its immunoglobulins, epithelial growth factors and more, helps protect against leaky gut and small intestine damage in SIBO.  For brands of Colostrum that I have used and like, including non-dairy options: see my SIBO Symptomatic Relief Handout under Diarrhea. 
  • Management of small intestinal bacterial overgrowth by pediatric gastroenterologists in Spain  PMID: 33371710
  • Management of small intestinal bacterial overgrowth by pediatric gastroenterologists in Spain  PMID: 33371710
Antibiotics  
  • Antibiotic treatment for small intestinal bacterial overgrowth: Is a cocktail better than a single?  PMID: 33951351
  • ​The effectiveness of rotating versus single course antibiotics for small intestinal bacterial overgrowth  PMID: 34241973
Antibiotics: Rifaximin
  • Rifaximin  PMID: 32966000
  • Bifidobacterium longum W11: Uniqueness and individual or combined clinical use in association with rifaximin  PMID: 33745570
  • Serotonin Pathway of Tryptophan Metabolism in Small Intestinal Bacterial Overgrowth-A Pilot Study with Patients Diagnosed with Lactulose Hydrogen Breath Test and Treated with Rifaximin  PMID: 34065903
  • Efficacy of rifaximin in treating with small intestine bacterial overgrowth: a systematic review and meta-analysis  PMID: 34767484
  • Rifaximin-mediated gut microbiota regulation modulates the function of microglia and protects against CUMS-induced depression-like behaviors in adolescent rat  PMID: 34736493
Elemental Diet 
  • Homemade Elemental Diet to Treat Intestinal Methanogen Overgrowth: A Case Report.
Herbal Antibiotics  
  • NEW Chinese herbal medicine for the treatment of small intestinal bacterial overgrowth (SIBO): A protocol for systematic review and meta-analysis.  PMID: 33371127
FMT (Fecal Microbiota Transplantation) 
  • Clinical efficacy of fecal microbiota transplantation for patients with small intestinal bacterial overgrowth: a randomized, placebo-controlled clinic study.  PMID: 33549047 
Diet 
  • Impact of Diet on Symptoms of the Irritable Bowel Syndrome.  PMID: 33572262
  • Homemade Elemental Diet to Treat Intestinal Methanogen Overgrowth: A Case Report.
 Prokinetics
  • Deja-vu? Neural and behavioural effects of the 5-HT(4) receptor agonist, prucalopride, in a hippocampal-dependent memory task.  PMID: 34602607 ..."these findings demonstrate the potential of 5-HT4-receptor activation [prucalopride] for cognitive enhancement in humans.”

Diet: FODMAP
  • Treatment efficacy of a low FODMAP diet compared to a low lactose diet in IBS patients: A randomized, cross-over designed study.  PMID: 33183577 
  • Low fermentable oligosaccharide, disaccharide, monosaccharide, and polyol diet in patients with diarrhea-predominant irritable bowel syndrome: A prospective, randomized trial.  PMID: 33464683 
  • Methane and fatty acid metabolism pathways are predictive of Low-FODMAP diet efficacy for patients with irritable bowel syndrome.  PMID: 33504454 
  • Habitual FODMAP Intake in Relation to Symptom Severity and Pattern in Patients with Irritable Bowel Syndrome.  PMID: 33374779  
  • Irritable Bowel Syndrome: Food as a Friend or Foe?  PMID: 33518164 
  • Fundamental study on changes in the FODMAP profile of cereals, pseudo-cereals, and pulses during the malting process.  DOI 10.1016/j.foodchem.2020.128549 
  • What is the optimal FODMAP threshold in IBS?  PMID: 33624857
  • Dietary interventions and irritable bowel syndrome - what really works?  PMID: 33332914
  • Editorial: defining a microbial signature to predict non-response to a FODMAP diet-a step closer or is it?  PMID: 33566410
  • Editorial: defining a microbial signature to predict non-response to a low FODMAP diet-a step closer or is it? Authors' reply.  PMID: 33566399
  • Efficacy of a low-FODMAP diet in adult irritable bowel syndrome: a systematic review and meta-analysis.  PMID: 33585949
  • The role of diet in the pathophysiology and management of irritable bowel syndrome.  PMID: 33666892
  • Long-term symptom severity in people with irritable bowel syndrome following dietetic treatment in primary care: A service evaluation.  PMID: 33761153
  • Reducing FODMAPs and improving bread quality using type II sourdough with selected starter cultures.  PMID: 33653200
  • Low fermentable oligosaccharides, disaccharides, monosaccharides, and polyols diet compared with traditional dietary advice for diarrhea-predominant irritable bowel syndrome: a parallel-group, randomized controlled trial with analysis of clinical and microbiological factors associated with patient outcomes.  PMID: 33740048
  • FODMAP Fingerprinting of Bakery Products and Sourdoughs: Quantitative Assessment and Content Reduction through Fermentation  PMID: 33921672
  • The low FODMAP diet for IBS; A multicentre UK study assessing long term follow up  PMID: 34083153
  • Low FODMAP (fermentable oligo-, di-, monosaccharides, and polyol) diet goes global  PMID: 33851195
  • Diarrhea Predominant-Irritable Bowel Syndrome (IBS-D): Effects of Different Nutritional Patterns on Intestinal Dysbiosis and Symptoms  PMID: 33946961
  • Low fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAP) diet is associated with increased risk of uninvestigated chronic dyspepsia and its symptoms in adults  PMID: 33971708
  • The Relationship between Low Serum Vitamin D Levels and Altered Intestinal Barrier Function in Patients with IBS Diarrhoea Undergoing a Long-Term Low-FODMAP Diet: Novel Observations from a Clinical Trial  PMID: 33801020
  • Gluten and FODMAPs Relationship with Mental Disorders: Systematic Review  PMID: 34072914
  • Intestinal microbiota fingerprint in subjects with irritable bowel syndrome responders to a low FODMAP diet  PMID: 33877245
  • Better response to low FODMAP diet in DGBI patients with pronounced hydrogen response to a nutrient challenge test  PMID: 34107550
  • Epigastric symptom response to low FODMAP dietary advice compared with standard dietetic advice in individuals with functional dyspepsia  PMID: 33844408
  • High-Fat Foods and FODMAPs Containing Gluten Foods Primarily Contribute to Symptoms of Irritable Bowel Syndrome in Korean Adults  PMID: 33920966
  • Physicochemical and nutritional properties of high protein emulsion-type lupin-based model milk alternatives: effect of protein source and homogenization pressure  PMID: 33792053 Commentary: Lupine milk is high protein and low fodmap.
  • Characteristics and properties of fibres suitable for a low FODMAP diet- an overview  doi.org/10.1016/j.tifs.2021.04.023
  • Low Fodmap Diet & Prebiotic β-Galactooligosaccharides Improve Irritable Bowel Syndrome with no Impact on α-Diversity and Response to Low Fodmap Diet is Predicted by Urine and Fecal Metabolites: A Randomised Controlled Trial  doi.org/10.1016/S0016-5085(18)32410-7
  • LOW FODMAP DIET ADHERENCE IS HIGH AND POSITIVELY IMPACTS NUTRITIONAL INTAKE AND DIET QUALITY IN CHILDREN WITH IRRITABLE BOWEL SYNDROME (IBS)  doi.org/10.1016/S0016-5085(21)02515-4
  • β-fructosidase FosE activity in Lactobacillus paracasei regulates fructan degradation during sourdough fermentation and total FODMAP levels in steamed bread  doi.org/10.1016/j.lwt.2021.111294
  • THE ROLE OF ILLNESS PERCEPTIONS IN TREATMENT RESPONSE OF ADULTS WITH IBS UNDERGOING LOW FODMAP DIET INTERVENTION: A PROSPECTIVE STUDY.  doi.org/10.1016/S0016-5085(21)02334-9
  • MAST-CELL ACTIVATION LEADING TO COLONIC BARRIER DYSFUNCTION FOLLOWING HIGH-FODMAP DIET IS MEDIATED VIA LIPOPOLYSACCHARIDE  doi.org/10.1016/S0016-5085(21)00924-0
  • EVALUATING THE FACTUAL ACCURACY OF LOW FODMAP DIETARY CONTENT ON INSTAGRAM: A BLINDED, DIETITIAN-RATED ANALYSIS  doi.org/10.1016/S0016-5085(21)02490-2
  • FODMAPS, BUT NOT GLUTEN, ELICIT MODEST SYMPTOMS OF IRRITABLE BOWEL SYNDROME: DOUBLE-BLIND, PLACEBO-CONTROLLED RANDOMISED THREE-WAY CROSSOVER TRIAL  doi.org/10.1016/S0016-5085(21)00927-6
  • ARE ALL FODMAPS CREATED EQUAL? A BLINDED, RANDOMIZED REINTRODUCTION TRIAL TO DETERMINE WHICH FODMAPS DRIVE CLINICAL RESPONSE IN IBS PATIENTS  doi.org/10.1016/S0016-5085(21)02493-8
  • FODMAP Consumption by Adults from the French Population-Based NutriNet-Santé Cohort  PMID: 34224572  
  • Efficacy of a low FODMAP diet in irritable bowel syndrome: systematic review and network meta-analysis  PMID: 34376515 
  • Long-term personalized low FODMAP diet improves symptoms and maintains luminal Bifidobacteria abundance in irritable bowel syndrome  PMID: 34431172 
  • Better response to low FODMAP diet in disorders of gut-brain interaction patients with pronounced hydrogen response to a nutrient challenge test  PMID: 34107550 
  • Psychological and Gastrointestinal Symptoms of Patients with Irritable Bowel Syndrome Undergoing a Low-FODMAP Diet: The Role of the Intestinal Barrier  PMID: 34371976 
  • Influence of low FODMAP-gluten free diet on gut microbiota alterations and symptom severity in Iranian patients with irritable bowel syndrome  PMID: 34261437 
  • A Low-FODMAP Diet Improves the Global Symptoms and Bowel Habits of Adult IBS Patients: A Systematic Review and Meta-Analysis  PMID: 34490319 
  • Effect of Low FODMAPs Diet on Irritable Bowel Syndromes: A Systematic Review and Meta-Analysis of Clinical Trials  PMID: 34371973 
  • Correction to: Efficacy of a low-FODMAP diet in adult irritable bowel syndrome: a systematic review and meta-analysis  PMID: 34181070 
  • Diet Interventions for Irritable Bowel Syndrome: Separating the Wheat from the Chafe  PMID: 34304788 
  • Designing New Foods or Food Ingredients Targeting the Gut Microbiota to Reduce FODMAP-Induced Irritable Bowel Syndrome (IBS)  DOI:10.1016/B978-0-12-819265-8.00093-0
  • The FODMAP diet: more than just a symptomatic therapy?  PMID: 34810233
  • High FODMAP diet causes barrier loss via lipopolysaccharide-mediated mast cell activation  PMID: 34618688  "Our findings indicate that a HFM diet causes mast cell activation via LPS, which in turn leads to colonic barrier loss, and a LFM diet reverses these pathophysiologic mucosal changes."
  • Group education on the low FODMAP diet improves gastrointestinal symptoms but neither anxiety or depression in irritable bowel syndrome  PMID: 34705305
  • Effects of a low-FODMAP enteral formula on diarrhea on patients in the intensive care unit  PMID: 34858549
  • Two microbiota subtypes identified in irritable bowel syndrome with distinct responses to the low FODMAP diet  PMID: 34810234  "50% of IBS cases manifested a 'pathogenic' gut microbial signature. This shifted towards the healthy profile on the low FODMAP diet... with an increase in Bacteroidetes, a decrease in Frimicutes species and normalisation of primary metabolic genes."
  • Adult celiac disease with persistent IBS-type symptoms: a pilot study of an adjuvant FODMAP diet  PMID: 34659657
  • Lachancea fermentati FST 5.1: an alternative to baker's yeast to produce low FODMAP whole wheat bread  PMID: 34710210
  • Fermentable Oligosaccharides, Disaccharides, Monosaccharides and Polyols (FODMAPs) and cancer risk in the prospective NutriNet-Santé cohort  PMID: 34718693
  • FODMAPs, but not gluten, elicit modest symptoms of irritable bowel syndrome: a double-blind, placebo-controlled, randomized three-way crossover trial  PMID: 34617561
  • Supplementing dietary fibres with a low FODMAP diet in irritable bowel syndrome: a randomized controlled crossover trial  doi:10.1016/j.cgh.2021.12.016
  • Non-pharmacologic strategies for the management of intestinal inflammation  PMID: 34808552
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